human LBP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human LBP.
shADV-213714
Ad-h-LBP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human LBP (lipopolysaccharide binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BPIFD2
Description (Vector)
LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Gene ID
3929
Gene Name (Vector)
lipopolysaccharide binding protein
Gene Symbol
LBP
HGNC ID
HGNC:6517
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_004139
RefSeq Synonyms
NM_004139, BC022256,
Species
human
UniGene ID
Hs.154078
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.