human KYNU shRNA silencing Adenovirus

Name 
Ad-h-KYNU-shRNA
Cat No 
shADV-213620
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human KYNU.

shADV-213620
Ad-h-KYNU-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KYNU (kynureninase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
KYNUU
Description (Vector)
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants.
Gene ID
8942
Gene Name (Vector)
kynureninase
Gene Symbol
KYNU
HGNC ID
HGNC:6469
ORF Size (aa)
924
ORF Size (bp)
924 bp
RefSeq ID
NM_003937
RefSeq Synonyms
NM_003937, NM_001199241, NM_001032998, BC000879,
Species
human
UniGene ID
Hs.470126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.