human KRT80 shRNA silencing Adenovirus

Name 
Ad-h-KRT80-shRNA
Cat No 
shADV-213461
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human KRT80.

shADV-213461
Ad-h-KRT80-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT80 (keratin 80). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
KB20
Description (Vector)
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
Gene ID
144501
Gene Name (Vector)
keratin 80
Gene Symbol
KRT80
HGNC ID
HGNC:27056
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_182507
RefSeq Synonyms
NM_182507, NM_001081492, BC065180,
Species
human
UniGene ID
Hs.140978

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.