human IST1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human IST1.
shADV-212887
Ad-h-IST1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human IST1 (IST1, ESCRT-III associated factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hIST1; increased sodium tolerance 1 homolog; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; OLC1; overexpressed in lung cancer 1; putative MAPK-activating protein PM28
Description (eCommerce)
Increased sodium tolerance 1 homolog (IST1) is a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis [taken from NCBI Entrez Gene (Gene ID: 9798)].
Description (Vector)
IST1 encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
9798
Gene Name (eCommerce)
IST1, ESCRT-III associated factor
Gene Name (Vector)
IST1, ESCRT-III associated factor
Gene Symbol
IST1
HGNC ID
HGNC:28977
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
Protein Name (eCommerce)
IST1 homolog
RefSeq ID
NM_014761
RefSeq Synonyms
NM_014761, NM_001270979, NM_001270978, NM_001270977, NM_001270976, NM_001270975, BC103745, BC004359, BC000430, BC000116,
Research Areas
Cell Cycle,Cell Division,Golgi Apparatus
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Increased sodium tolerance 1 homolog (IST1) is a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis [taken from NCBI Entrez Gene (Gene ID: 9798)].
UniGene ID
Hs.232194
UniProt ID (eCommerce)
P53990
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.