human KCNJ4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KCNJ4.
shADV-212720
Ad-h-KCNJ4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNJ4 (potassium voltage-gated channel subfamily J member 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HIR; HIRK2; HRK1; IRK-3; IRK3; Kir2.3
Description (Vector)
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
3761
Gene Name (Vector)
potassium voltage-gated channel subfamily J member 4
Gene Symbol
KCNJ4
HGNC ID
HGNC:6265
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_004981
RefSeq Synonyms
NM_152868, NM_004981, BC113508, BC113506,
Species
human
UniGene ID
Hs.32505
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.