human EIF2AK1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF2AK1

Gene Name

eukaryotic translation initiation factor 2 alpha kinase 1

Gene ID

27102

Gene Synonyms

HCR; HRI

ORF Size

1893 bp

RefSeq#

NM_014413

Gene Description

EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.520205

HGNC ID

HGNC:24921