human ITGA4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ITGA4.
shADV-212481
Ad-h-ITGA4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ITGA4 (integrin subunit alpha 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD antigen CD49d; CD49 antigen-like family member D; CD49D; IA4; integrin alpha-4; integrin alpha-IV; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Description (eCommerce)
Integrin subunit alpha 4 (ITGA4) is a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling [taken from NCBI Entrez Gene (Gene ID: 3676)].
Description (Vector)
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.
Gene ID
3676
Gene Name (eCommerce)
integrin subunit alpha 4
Gene Name (Vector)
integrin subunit alpha 4
Gene Symbol
ITGA4
HGNC ID
HGNC:6140
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3099
ORF Size (bp)
3099 bp
Protein Name (eCommerce)
Integrin alpha-4
RefSeq ID
NM_000885
RefSeq Synonyms
NM_001316312, NM_000885, BC156712, BC146277, BC080190,
Research Areas
Cardiac Development,Cardiology,Cardiomyopathy,Cardiovascular,Cytoskeleton,Immunology,PI3K/Akt Signaling,Signal Transduction,VEGF Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,signal_transduction
Species
human
Target Sentence
Integrin subunit alpha 4 (ITGA4) is a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling [taken from NCBI Entrez Gene (Gene ID: 3676)].
UniGene ID
Hs.440955
UniProt ID (eCommerce)
P13612
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.