human ITGA2B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ITGA2B.
shADV-212475
Ad-h-ITGA2B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ITGA2B (integrin subunit alpha 2b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93
Description (Vector)
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Gene ID
3674
Gene Name (Vector)
integrin subunit alpha 2b
Gene Symbol
ITGA2B
HGNC ID
HGNC:6138
ORF Size (aa)
3120
ORF Size (bp)
3120 bp
RefSeq ID
NM_000419
RefSeq Synonyms
NM_000419, BC126442, BC117443,
Species
human
UniGene ID
Hs.411312
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.