human INHBB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human INHBB.
shADV-212271
Ad-h-INHBB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human INHBB (inhibin beta B subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
Gene ID
3625
Gene Name (Vector)
inhibin beta B subunit
Gene Symbol
INHBB
HGNC ID
HGNC:6067
ORF Size (aa)
1224
ORF Size (bp)
1224 bp
RefSeq ID
NM_002193
RefSeq Synonyms
NM_002193, BC030029,
Species
human
UniGene ID
Hs.1735
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.