human INHBB shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-212271
Availability:
6-8 weeks
Name:
AAV-h-INHBB-shRNA
This is an AAV expressing shRNA for silencing of Human INHBB.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- INHBB
- Gene Name
- inhibin beta B subunit
- Gene ID
- 3625
- ORF Size
- 1224 bp
- RefSeq#
- NM_002193
- Gene Description
- The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
- UniGene ID
- Hs.1735
- HGNC ID
- HGNC:6067
Related Products
Product | Cat No. |
---|---|
AAV-h-INHBB | AAV-212271 |
AAV-m-INHBB | AAV-262244 |
Ad-h-INHBB | ADV-212271 |
Ad-m-INHBB | ADV-262244 |
AAV-m-INHBB-shRNA | shAAV-262244 |
Ad-h-INHBB-shRNA | shADV-212271 |
Ad-m-INHBB-shRNA | shADV-262244 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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