human ING4 shRNA silencing Adenovirus

Name 
Ad-h-ING4-shRNA
Cat No 
shADV-212266
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ING4.

shADV-212266
Ad-h-ING4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ING4 (inhibitor of growth family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
my036; p29ING4
Description (Vector)
ING4 encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Gene ID
51147
Gene Name (Vector)
inhibitor of growth family member 4
Gene Symbol
ING4
HGNC ID
HGNC:19423
ORF Size (aa)
750
ORF Size (bp)
750 bp
RefSeq ID
NM_016162
RefSeq Synonyms
NM_016162, NM_001127586, NM_001127585, NM_001127584, NM_001127583, NM_001127582, BC095434, BC007781,
Species
human
UniGene ID
Hs.524210

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.