human HTR2A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HTR2A.
shADV-211689
Ad-h-HTR2A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HTR2A (5-hydroxytryptamine receptor 2A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5-HT2A; HTR2
Description (Vector)
HTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3356
Gene Name (Vector)
5-hydroxytryptamine receptor 2A
Gene Symbol
HTR2A
HGNC ID
HGNC:5293
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
RefSeq ID
NM_000621
RefSeq Synonyms
NM_001165947, NM_000621, BC096839, BC074849, BC074848, BC069576, BC069356,
Species
human
UniGene ID
Hs.654586
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.