human HELLS shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HELLS

Gene Name

helicase, lymphoid-specific

Gene ID

3070

Gene Synonyms

ICF4; LSH; Nbla10143; PASG; SMARCA6

ORF Size

2514 bp

RefSeq#

NM_018063

Gene Description

HELLS encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

UniGene ID

Hs.655830

HGNC ID

HGNC:4861