human HDLBP shRNA silencing Adenovirus

Name 
Ad-h-HDLBP-shRNA
Cat No 
shADV-210910
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HDLBP.

shADV-210910
Ad-h-HDLBP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HDLBP (high density lipoprotein binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HBP; HDL-binding protein; High density lipoprotein-binding protein; PRO2900; VGL; vigilin
Description (eCommerce)
Vigilin binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. Vigilin also binds RNA and can induce heterochromatin formation [taken from NCBI Entrez Gene (Gene ID: 3069)].
Description (Vector)
HDLBP binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
3069
Gene Name (eCommerce)
high density lipoprotein binding protein
Gene Name (Vector)
high density lipoprotein binding protein
Gene Symbol
HDLBP
HGNC ID
HGNC:4857
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3807
ORF Size (bp)
3807 bp
Protein Name (eCommerce)
Vigilin
RefSeq ID
NM_005336
RefSeq Synonyms
NM_203346, NM_005336, NM_001320967, NM_001320966, NM_001320965, NM_001243900, BC001179,
Research Areas
Metabolism/Metabolic Process,RNA Binding,Transport
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Vigilin binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. Vigilin also binds RNA and can induce heterochromatin formation [taken from NCBI Entrez Gene (Gene ID: 3069)].
UniGene ID
Hs.471851
UniProt ID (eCommerce)
Q00341

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.