human HDAC8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HDAC8.
shADV-210894
Ad-h-HDAC8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HDAC8 (histone deacetylase 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS
Description (Vector)
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
55869
Gene Name (Vector)
histone deacetylase 8
Gene Symbol
HDAC8
HGNC ID
HGNC:13315
ORF Size (aa)
1134
ORF Size (bp)
1134 bp
RefSeq ID
NM_018486
RefSeq Synonyms
NM_018486, NM_001166448, NM_001166422, NM_001166420, NM_001166419, NM_001166418, BC050433,
Species
human
UniGene ID
Hs.310536
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.