human HCN4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HCN4.
shADV-210875
Ad-h-HCN4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HCN4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SSS2
Description (Vector)
HCN4 encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
Gene ID
10021
Gene Name (Vector)
hyperpolarization activated cyclic nucleotide gated potassium channel 4
Gene Symbol
HCN4
HGNC ID
HGNC:16882
ORF Size (aa)
3609
ORF Size (bp)
3609 bp
RefSeq ID
NM_005477
RefSeq Synonyms
NM_005477, BC172471, BC156298,
Species
human
UniGene ID
Hs.86941
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.