human GZMM shRNA silencing Adenovirus

Name 
Ad-h-GZMM-shRNA
Cat No 
shADV-210721
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human GZMM.

shADV-210721
Ad-h-GZMM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GZMM (granzyme M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LMET1; MET1
Description (Vector)
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
3004
Gene Name (Vector)
granzyme M
Gene Symbol
GZMM
HGNC ID
HGNC:4712
ORF Size (aa)
774
ORF Size (bp)
774 bp
RefSeq ID
NM_005317
RefSeq Synonyms
NM_005317, NM_001258351, BC025701,
Species
human
UniGene ID
Hs.465511

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.