human GYS1 shRNA silencing Adenovirus

Name 
Ad-h-GYS1-shRNA
Cat No 
shADV-210713
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GYS1.

shADV-210713
Ad-h-GYS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GYS1 (glycogen synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
glycogen starch synthase, muscle; glycogen synthase 1 (muscle); GSY; GYS
Description (eCommerce)
Glycogen synthase 1 (muscle) (GYS1) catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in the GYS1 gene are associated with muscle glycogen storage disease [taken from NCBI Entrez Gene (Gene ID: 2997)].
Description (Vector)
GYS1 catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
2997
Gene Name (eCommerce)
glycogen synthase 1
Gene Name (Vector)
glycogen synthase 1
Gene Symbol
GYS1
HGNC ID
HGNC:4706
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2022
ORF Size (bp)
2022 bp
Protein Name (eCommerce)
Glycogen [starch] synthase, muscle
RefSeq ID
NM_002103
RefSeq Synonyms
NM_002103, NM_001161587, BC007688, BC003182, BC002617,
Research Areas
Cardiac Development,Cardiology,Cardiovascular,Immunology,Insulin Signaling,Metabolism/Metabolic Process,PI3K/Akt Signaling,SCF-KIT Signaling,Signal Transduction
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,metabolism,signal_transduction,stem_cell_biology
Species
human
Target Sentence
Glycogen synthase 1 (muscle) (GYS1) catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in the GYS1 gene are associated with muscle glycogen storage disease [taken from NCBI Entrez Gene (Gene ID: 2997)].
UniGene ID
Hs.386225
UniProt ID (eCommerce)
P13807

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.