human GUCY2F shRNA silencing Adenovirus

Name 
Ad-h-GUCY2F-shRNA
Cat No 
shADV-210693
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human GUCY2F.

shADV-210693
Ad-h-GUCY2F-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GUCY2F (guanylate cyclase 2F, retinal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CYGF; GC-F; GUC2DL; GUC2F; RETGC-2; ROS-GC2
Description (Vector)
GUCY2F is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
Gene ID
2986
Gene Name (Vector)
guanylate cyclase 2F, retinal
Gene Symbol
GUCY2F
HGNC ID
HGNC:4691
ORF Size (aa)
3327
ORF Size (bp)
3327 bp
RefSeq ID
NM_001522
RefSeq Synonyms
NM_001522, BC156674,
Species
human
UniGene ID
Hs.123074

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.