human GSS shRNA silencing Adenovirus

Name 
Ad-h-GSS-shRNA
Cat No 
shADV-210591
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GSS.

shADV-210591
Ad-h-GSS-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GSS (glutathione synthetase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GSHS; HEL-S-64p; HEL-S-88n
Description (Vector)
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Gene ID
2937
Gene Name (Vector)
glutathione synthetase
Gene Symbol
GSS
HGNC ID
HGNC:4624
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
RefSeq ID
NM_000178
RefSeq Synonyms
NM_001322495, NM_001322494, NM_000178, BC007927,
Species
human
UniGene ID
Hs.82327

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.