human GRIK3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GRIK3.
shADV-210516
Ad-h-GRIK3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GRIK3 (glutamate ionotropic receptor kainate type subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EAA5; GLR7; GluK3; GLUR7; GluR7a
Description (Vector)
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
Gene ID
2899
Gene Name (Vector)
glutamate ionotropic receptor kainate type subunit 3
Gene Symbol
GRIK3
HGNC ID
HGNC:4581
ORF Size (aa)
2760
ORF Size (bp)
2760 bp
RefSeq ID
NM_000831
RefSeq Synonyms
NM_000831, BC156721,
Species
human
UniGene ID
Hs.128848
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.