human GNS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GNS.
shADV-210146
Ad-h-GNS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GNS (glucosamine (N-acetyl)-6-sulfatase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
G6S
Description (Vector)
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Gene ID
2799
Gene Name (Vector)
glucosamine (N-acetyl)-6-sulfatase
Gene Symbol
GNS
HGNC ID
HGNC:4422
ORF Size (aa)
1659
ORF Size (bp)
1659 bp
RefSeq ID
NM_002076
RefSeq Synonyms
NM_002076, BC012482,
Species
human
UniGene ID
Hs.334534
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.