human GLRX2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GLRX2.
shADV-209998
Ad-h-GLRX2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GLRX2 (glutaredoxin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-133; GRX2
Description (Vector)
GLRX2 is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.
Gene ID
51022
Gene Name (Vector)
glutaredoxin 2
Gene Symbol
GLRX2
HGNC ID
HGNC:16065
ORF Size (aa)
375
RefSeq ID
NM_016066
RefSeq Synonyms
NM_197962, NM_016066, NM_001319291, NM_001243399, BC028113,
Species
human
UniGene ID
Hs.458283
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.