human GJB3 shRNA silencing Adenovirus

Name 
Ad-h-GJB3-shRNA
Cat No 
shADV-209925
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GJB3.

shADV-209925
Ad-h-GJB3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GJB3 (gap junction protein beta 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
71
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CX31; DFNA2; DFNA2B; EKV
Description (Vector)
GJB3 is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
2707
Gene Name (Vector)
gap junction protein beta 3
Gene Symbol
GJB3
HGNC ID
HGNC:4285
ORF Size (aa)
813
ORF Size (bp)
813 bp
RefSeq ID
NM_024009
RefSeq Synonyms
NM_024009, NM_001005752, BC110640, BC012918,
Species
human
UniGene ID
Hs.522561

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.