human GGA2 shRNA silencing Adenovirus

Name 
Ad-h-GGA2-shRNA
Cat No 
shADV-209838
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GGA2.

shADV-209838
Ad-h-GGA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
VEAR
Description (Vector)
GGA2 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Gene ID
23062
Gene Name (Vector)
golgi associated, gamma adaptin ear containing, ARF binding protein 2
Gene Symbol
GGA2
HGNC ID
HGNC:16064
ORF Size (aa)
1842
ORF Size (bp)
1842 bp
RefSeq ID
NM_015044
RefSeq Synonyms
NM_015044, BC000284,
Species
human
UniGene ID
Hs.460336

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.