human GFI1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GFI1.
shADV-209819
Ad-h-GFI1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GFI1 (growth factor independent 1 transcriptional repressor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GFI-1; GFI1A; SCN2; ZNF163
Description (Vector)
GFI1 encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Gene ID
2672
Gene Name (Vector)
growth factor independent 1 transcriptional repressor
Gene Symbol
GFI1
HGNC ID
HGNC:4237
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_005263
RefSeq Synonyms
NM_005263, NM_001127216, NM_001127215, BC074867, BC074866, BC032751,
Species
human
UniGene ID
Hs.73172
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.