human GEMIN8 shRNA silencing Adenovirus

Name 
Ad-h-GEMIN8-shRNA
Cat No 
shADV-209810
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GEMIN8.

shADV-209810
Ad-h-GEMIN8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GEMIN8 (gem nuclear organelle associated protein 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FAM51A1
Description (Vector)
GEMIN8 is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
54960
Gene Name (Vector)
gem nuclear organelle associated protein 8
Gene Symbol
GEMIN8
HGNC ID
HGNC:26044
ORF Size (aa)
729
ORF Size (bp)
729 bp
RefSeq ID
NM_017856
RefSeq Synonyms
NM_017856, NM_001042480, NM_001042479, BC020785, BC014324, BC003607,
Species
human
UniGene ID
Hs.592237

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.