human GCNT2 shRNA silencing Adenovirus

Name
Ad-h-GCNT2-shRNA

Cat No
shADV-209757

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GCNT2.

shADV-209757

Ad-h-GCNT2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GCNT2 (glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

bA360O19.2; bA421M1.1; CCAT; CTRCT13; GCNT2C; GCNT5; IGNT; II; NACGT1; NAGCT1; ULG3

Description (Vector)

GCNT2 encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID

2651

Gene Name (Vector)

glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)

Gene Symbol

GCNT2

HGNC ID

HGNC:4204

ORF Size (aa)

1209

ORF Size (bp)

1209 bp

RefSeq ID

NM_145649

RefSeq Synonyms

NM_145655, NM_145649, NM_001491, BC130524, BC074802, BC074801,

Species

human

UniGene ID

Hs.519884

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.