human GATA3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GATA3.
shADV-209677
Ad-h-GATA3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GATA3 (GATA binding protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GATA-binding factor 3; HDR; HDRS; trans-acting T-cell-specific transcription factor GATA-3
Description (eCommerce)
GATA binding protein 3 (GATA3) is a transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
Description (Vector)
GATA3 encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Gene ID
2625
Gene Name (eCommerce)
GATA binding protein 3
Gene Name (Vector)
GATA binding protein 3
Gene Symbol
GATA3
HGNC ID
HGNC:4172
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
Protein Name (eCommerce)
Trans-acting T-cell-specific transcription factor GATA-3
RefSeq ID
NM_002051
RefSeq Synonyms
NM_002051, NM_001002295, BC006793, BC003070,
Research Areas
Apoptosis,Axon Guidance,Cancer,Cardiac Development,Cardiology,Cardiovascular,Cell Cycle,Estrogen Signaling,FGF Signaling,Histone Modification,Host-Virus Interactions,IFN Signaling,Immunology,Interleukin Signaling,mTOR Signaling,Neurobiology,Neurodevelopment,Notch Signaling,Response to Virus,Signal Transduction,T-cell Receptor Signaling,Transcription Factor/Regulator,Wnt Signaling,Zinc-finger
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
GATA binding protein 3 (GATA3) is a transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
UniGene ID
Hs.524134
UniProt ID (eCommerce)
P23771
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.