human GALNS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GALNS.
shADV-209581
Ad-h-GALNS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GALNS (galactosamine (N-acetyl)-6-sulfatase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GalN6S; GALNAC6S; GAS; MPS4A
Description (Vector)
GALNS encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.
Gene ID
2588
Gene Name (Vector)
galactosamine (N-acetyl)-6-sulfatase
Gene Symbol
GALNS
HGNC ID
HGNC:4122
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_000512
RefSeq Synonyms
NM_001323544, NM_001323543, NM_000512, BC056151, BC050684,
Species
human
UniGene ID
Hs.271383
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.