human GABRA1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GABRA1.
shADV-209506
Ad-h-GABRA1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GABRA1 (gamma-aminobutyric acid type A receptor alpha1 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ECA4; EIEE19; EJM; EJM5
Description (Vector)
GABRA1 encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Gene ID
2554
Gene Name (Vector)
gamma-aminobutyric acid type A receptor alpha1 subunit
Gene Symbol
GABRA1
HGNC ID
HGNC:4075
ORF Size (aa)
1371
ORF Size (bp)
1371 bp
RefSeq ID
NM_000806
RefSeq Synonyms
NM_001127648, NM_001127647, NM_001127646, NM_001127645, NM_001127644, NM_001127643, NM_000806, BC030696,
Species
human
UniGene ID
Hs.175934
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.