human FPGS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FPGS.
shADV-209293
Ad-h-FPGS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FPGS (folylpolyglutamate synthase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
FPGS encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms.
Gene ID
2356
Gene Name (Vector)
folylpolyglutamate synthase
Gene Symbol
FPGS
HGNC ID
HGNC:3824
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
RefSeq ID
NM_004957
RefSeq Synonyms
NM_004957, NM_001288803, NM_001018078, BC064393,
Species
human
UniGene ID
Hs.335084
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.