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human FPGS Adenovirus

Name 
Ad-h-FPGS
Cat No 
ADV-209293
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human FPGS.

ADV-209293
Ad-h-FPGS

Ready-to-use Adenovirus expressing Human FPGS (folylpolyglutamate synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
FPGS encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms.
Gene ID
2356
Gene Name (Vector)
folylpolyglutamate synthase
Gene Symbol
FPGS
HGNC ID
HGNC:3824
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
RefSeq ID
NM_004957
RefSeq Synonyms
NM_004957, NM_001288803, NM_001018078, BC064393,
Species
human
UniGene ID
Hs.335084

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.