human FOXN3 shRNA silencing Adenovirus

Name 
Ad-h-FOXN3-shRNA
Cat No 
shADV-209269
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human FOXN3.

shADV-209269
Ad-h-FOXN3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FOXN3 (forkhead box N3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C14orf116; checkpoint suppressor 1; CHES1; forkhead box protein N3; PRO1635
Description (eCommerce)
Forkhead box protein N3 (FOXN3) functions as a transcriptional repressor. FOXN3 is also called checkpoint suppressor 1 (CHES1) and may be involved in DNA damage-inducible cell cycle arrests (checkpoints).
Description (Vector)
FOXN3 is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.
Gene ID
1112
Gene Name (eCommerce)
forkhead box N3
Gene Name (Vector)
forkhead box N3
Gene Symbol
FOXN3
HGNC ID
HGNC:1928
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
Protein Name (eCommerce)
Forkhead box protein N3
RefSeq ID
NM_005197
RefSeq Synonyms
NM_005197, NM_001085471, BC010460, BC007506,
Research Areas
Cell Cycle,DNA Damage/Repair,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Forkhead box protein N3 (FOXN3) functions as a transcriptional repressor. FOXN3 is also called checkpoint suppressor 1 (CHES1) and may be involved in DNA damage-inducible cell cycle arrests (checkpoints).
UniGene ID
Hs.621371
UniProt ID (eCommerce)
O00409

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.