human FMO5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FMO5.
shADV-209184
Ad-h-FMO5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FMO5 (flavin containing monooxygenase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
Gene ID
2330
Gene Name (Vector)
flavin containing monooxygenase 5
Gene Symbol
FMO5
HGNC ID
HGNC:3773
ORF Size (aa)
858
ORF Size (bp)
858 bp
RefSeq ID
NM_001461
RefSeq Synonyms
NM_001461, NM_001144830, NM_001144829, BC035687,
Species
human
UniGene ID
Hs.642706
Recently Viewed Products
Ad-h-AMY1B-shRNA
Cat No: shADV-200886
AAV-m-AMZ1-shRNA
Cat No: shAAV-260373
AAV-h-SLC37A4-shRNA
Cat No: shAAV-229603
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.