human FHIT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FHIT.
shADV-209008
Ad-h-FHIT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FHIT (fragile histidine triad). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AP3Aase; FRA3B
Description (Vector)
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Gene ID
2272
Gene Name (Vector)
fragile histidine triad
Gene Symbol
FHIT
HGNC ID
HGNC:3701
ORF Size (aa)
444
RefSeq ID
NM_002012
RefSeq Synonyms
NM_002012, NM_001320901, NM_001320900, NM_001320899, NM_001166243, BC032336,
Species
human
UniGene ID
Hs.715597
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.