human FGG shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FGG.
shADV-208999
Ad-h-FGG-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FGG (fibrinogen gamma chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Gene ID
2266
Gene Name (Vector)
fibrinogen gamma chain
Gene Symbol
FGG
HGNC ID
HGNC:3694
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
RefSeq ID
NM_000509
RefSeq Synonyms
NM_021870, NM_000509, BC021674, BC007044,
Species
human
UniGene ID
Hs.546255
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.