human FBXO32 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FBXO32.
shADV-208801
Ad-h-FBXO32-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FBXO32 (F-box protein 32). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Fbx32; MAFbx
Description (Vector)
FBXO32 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
114907
Gene Name (Vector)
F-box protein 32
Gene Symbol
FBXO32
HGNC ID
HGNC:16731
ORF Size (aa)
633
ORF Size (bp)
633 bp
RefSeq ID
NM_058229
RefSeq Synonyms
NM_148177, NM_058229, NM_001242463, BC120964, BC120963, BC024030,
Species
human
UniGene ID
Hs.403933
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.