human FAM175A shRNA silencing Adenovirus

Name
Ad-h-FAM175A-shRNA

Cat No
shADV-208489

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human FAM175A.

shADV-208489

Ad-h-FAM175A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FAM175A (family with sequence similarity 175 member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

No

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ABRA1; abraxas protein; BRCA1-A complex subunit Abraxas; BRCA1-A complex subunit Abraxas 1; CCDC98; coiled-coil domain containing 98; Coiled-coil domain-containing protein 98; FAM175A; family with sequence similarity 175 member A; Protein FAM175A

Description (eCommerce)

Abraxas was identified in a phosphopeptide affinity proteomic and mass spec analysis as a protein that bound directly to the BRCA1 BRCT repeat. Along with RAP80, Abraxas was required to form a complex with BRCA1 for the DNA damage response.

Gene ID

84142

Gene Name (eCommerce)

abraxas 1, BRCA1 A complex subunit

Gene Name (Vector)

family with sequence similarity 175 member A

Gene Symbol

FAM175A

HGNC ID

HGNC:25829

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

903

ORF Size (bp)

903 bp

Protein Name (eCommerce)

BRCA1-A complex subunit Abraxas

RefSeq ID

NM_139076

RefSeq Synonyms

NM_139076, NM_001345962, BC039573, BC016905,

Research Areas

Cell Biology,Cell Cycle,DNA Damage/Repair,Homologous Recombination,Signal Transduction,Ubiquitination

Research Areas (Faceted)

signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation

Species

human

Target Sentence

Abraxas was identified in a phosphopeptide affinity proteomic and mass spec analysis as a protein that bound directly to the BRCA1 BRCT repeat. Along with RAP80, Abraxas was required to form a complex with BRCA1 for the DNA damage response.

UniGene ID

Hs.334772

UniProt ID (eCommerce)

Q6UWZ7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.