human F2RL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human F2RL1.
shADV-208224
Ad-h-F2RL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human F2RL1 (F2R like trypsin receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GPR11; PAR2
Description (Vector)
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
Gene ID
2150
Gene Name (Vector)
F2R like trypsin receptor 1
Gene Symbol
F2RL1
HGNC ID
HGNC:3538
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
RefSeq ID
NM_005242
RefSeq Synonyms
NM_005242, BC018130, BC012453,
Species
human
UniGene ID
Hs.154299
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.