human EZR shRNA silencing Adenovirus

Name
Ad-h-EZR-shRNA

Cat No
shADV-208213

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human EZR.

shADV-208213

Ad-h-EZR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EZR (ezrin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CVIL; CVL; HEL-S-105; VIL2

Description (Vector)

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Gene ID

7430

Gene Name (Vector)

ezrin

Gene Symbol

EZR

HGNC ID

HGNC:12691

ORF Size (aa)

1761

ORF Size (bp)

1761 bp

RefSeq ID

NM_003379

RefSeq Synonyms

NM_003379, NM_001111077, BC068458, BC013903,

Species

human

UniGene ID

Hs.487027

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.