human ERAP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ERAP1.
shADV-208037
Ad-h-ERAP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ERAP1 (endoplasmic reticulum aminopeptidase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
Description (Vector)
ERAP1 is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
51752
Gene Name (Vector)
endoplasmic reticulum aminopeptidase 1
Gene Symbol
ERAP1
HGNC ID
HGNC:18173
ORF Size (aa)
2826
ORF Size (bp)
2826 bp
RefSeq ID
NM_016442
RefSeq Synonyms
NM_016442, NM_001198541, NM_001040458, BC030775,
Species
human
UniGene ID
Hs.716426
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.