human EPS15L1 shRNA silencing Adenovirus

Name
Ad-h-EPS15L1-shRNA

Cat No
shADV-208023

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human EPS15L1.

shADV-208023

Ad-h-EPS15L1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

70

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; EPS15R; eps15-related protein

Description (eCommerce)

EPS15L1 (epidermal growth factor receptor substrate 15-like 1), also known as EPS15R (EPS15-related), is structurally related to the EPS15 protein, a protein involved in the receptor-mediated endocytosis of the EGF receptor. EPS15L1 and EPS15 both contain an EH (Eps15 homology) domain, a protein-protein interaction domain found in several proteins that participate in endocytosis, vesicle transport, and signal transduction.

Gene ID

58513

Gene Name (eCommerce)

epidermal growth factor receptor pathway substrate 15 like 1

Gene Name (Vector)

epidermal growth factor receptor pathway substrate 15 like 1

Gene Symbol

EPS15L1

HGNC ID

HGNC:24634

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2265

ORF Size (bp)

2265 bp

Protein Name (eCommerce)

Epidermal growth factor receptor substrate 15-like 1

RefSeq ID

NM_021235

RefSeq Synonyms

NM_021235, NM_001258376, NM_001258375, NM_001258374, BC142716, BC131590,

Research Areas

Cancer,EGFR Signaling,EGFR Signaling in Cancer,Signal Transduction

Research Areas (Faceted)

cancer,signal_transduction,cancer,signal_transduction

Species

human

Target Sentence

EPS15L1 (epidermal growth factor receptor substrate 15-like 1), also known as EPS15R (EPS15-related), is structurally related to the EPS15 protein, a protein involved in the receptor-mediated endocytosis of the EGF receptor. EPS15L1 and EPS15 both contain an EH (Eps15 homology) domain, a protein-protein interaction domain found in several proteins that participate in endocytosis, vesicle transport, and signal transduction.

UniGene ID

Hs.654639

UniProt ID (eCommerce)

Q9UBC2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.