human EIF3M shRNA silencing Adenovirus

Name 
Ad-h-EIF3M-shRNA
Cat No 
shADV-207763
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human EIF3M.

shADV-207763
Ad-h-EIF3M-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EIF3M (eukaryotic translation initiation factor 3 subunit M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B5; B5 receptor; dendritic cell protein; eIF3m; eukaryotic translation initiation factor 3 subunit M; fetal lung protein B5; GA17; hfl-B5; PCI domain containing 1 (herpesvirus entry mediator); PCI domain-containing protein 1; PCID1; TANGO7; transport and golgi organization 7 homolog
Description (eCommerce)
EIF3M is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of EIF3M are present in cancer cell lines. Inactivation of EIF3M has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes [taken from NCBI Entrez Gene (Gene ID: 10480)].
Description (Vector)
EIF3M encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome.
Gene ID
10480
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit M
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit M
Gene Symbol
EIF3M
HGNC ID
HGNC:24460
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit M
RefSeq ID
NM_006360
RefSeq Synonyms
NM_006360, NM_001307929, BC051292, BC019103,
Research Areas
Immunology,T-cell Receptor Signaling,Translational Control
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
EIF3M is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of EIF3M are present in cancer cell lines. Inactivation of EIF3M has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes [taken from NCBI Entrez Gene (Gene ID: 10480)].
UniGene ID
Hs.502244
UniProt ID (eCommerce)
Q7L2H7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.