human EIF2B3 shRNA silencing Adenovirus

Name 
Ad-h-EIF2B3-shRNA
Cat No 
shADV-207716
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human EIF2B3.

shADV-207716
Ad-h-EIF2B3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EIF-2B; EIF2Bgamma
Description (Vector)
EIF2B3 is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
8891
Gene Name (Vector)
eukaryotic translation initiation factor 2B subunit gamma
Gene Symbol
EIF2B3
HGNC ID
HGNC:3259
ORF Size (aa)
1206
ORF Size (bp)
1206 bp
RefSeq ID
NM_020365
RefSeq Synonyms
NM_020365, NM_001261418, NM_001166588, BC018728,
Species
human
UniGene ID
Hs.533549

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.