human EIF2AK2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EIF2AK2.
shADV-207705
Ad-h-EIF2AK2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIF2AK1; PKR; PPP1R83; PRKR
Description (Vector)
EIF2AK2 is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
5610
Gene Name (Vector)
eukaryotic translation initiation factor 2 alpha kinase 2
Gene Symbol
EIF2AK2
HGNC ID
HGNC:9437
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_002759
RefSeq Synonyms
NM_002759, NM_001135652, NM_001135651, BC143230, BC101475, BC093676,
Species
human
UniGene ID
Hs.131431
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.