human EEF1D shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EEF1D.
shADV-207600
Ad-h-EEF1D-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EEF1D (eukaryotic translation elongation factor 1 delta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
antigen NY-CO-4; EF1D; EF-1D; EF-1-delta; elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); FP1047
Description (eCommerce)
Elongation factor 1-delta (EF-1delta) is one of four subunits of the elongation factor-1 complex, a non-ribosomal complex that is involved in delivery of aminoacyl tRNAs to the ribosome. EF-1 is composed of EF-1alpha, EF-1beta, EF-1delta, and EF-1gamma. EF-1beta and EF-delta function as guanine nucleotide exchange factors and stimulate the exchange of GDP bound to EF-1 alpha for GTP.
Description (Vector)
EEF1D encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.
Gene ID
1936
Gene Name (eCommerce)
eukaryotic translation elongation factor 1 delta
Gene Name (Vector)
eukaryotic translation elongation factor 1 delta
Gene Symbol
EEF1D
HGNC ID
HGNC:3211
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1944
ORF Size (bp)
1944 bp
Protein Name (eCommerce)
Elongation factor 1-delta
RefSeq ID
NM_001960
RefSeq Synonyms
NM_032378, NM_001960, NM_001330646, NM_001317743, NM_001289950, NM_001195203, NM_001130057, NM_001130056, NM_001130055, NM_001130053, BC007847,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,NF-kB Signaling,Signal Transduction,Transcription Factor/Regulator,Translational Control
Research Areas (Faceted)
cell_biology,infectious_disease,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
Elongation factor 1-delta (EF-1delta) is one of four subunits of the elongation factor-1 complex, a non-ribosomal complex that is involved in delivery of aminoacyl tRNAs to the ribosome. EF-1 is composed of EF-1alpha, EF-1beta, EF-1delta, and EF-1gamma. EF-1beta and EF-delta function as guanine nucleotide exchange factors and stimulate the exchange of GDP bound to EF-1 alpha for GTP.
UniGene ID
Hs.686554
UniProt ID (eCommerce)
P29692
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.