human ECE1 shRNA silencing Adenovirus

Name 
Ad-h-ECE1-shRNA
Cat No 
shADV-207525
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ECE1.

shADV-207525
Ad-h-ECE1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ECE1 (endothelin converting enzyme 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ECE
Description (Vector)
ECE1 is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene ID
1889
Gene Name (Vector)
endothelin converting enzyme 1
Gene Symbol
ECE1
HGNC ID
HGNC:3146
ORF Size (aa)
2313
ORF Size (bp)
2313 bp
RefSeq ID
NM_001397
RefSeq Synonyms
NM_001397, NM_001113349, NM_001113348, NM_001113347, BC126257, BC117256,
Species
human
UniGene ID
Hs.195080

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.