human DYRK2 shRNA silencing Adenovirus

Name
Ad-h-DYRK2-shRNA

Cat No
shADV-207482

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DYRK2.

shADV-207482

Ad-h-DYRK2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.

Gene ID

8445

Gene Name (Vector)

dual specificity tyrosine phosphorylation regulated kinase 2

Gene Symbol

DYRK2

HGNC ID

HGNC:3093

ORF Size (aa)

1806

ORF Size (bp)

1806 bp

RefSeq ID

NM_003583

RefSeq Synonyms

NM_006482, NM_003583, BC006375, BC005809,

Species

human

UniGene ID

Hs.173135

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.