human DYRK1B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DYRK1B.
shADV-207479
Ad-h-DYRK1B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AOMS3; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; minibrain-related kinase; MIRK; mirk protein kinase
Description (eCommerce)
Minibrain-related kinase (mirk) is also known as DYRK1B (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B). Mirk is a member of the DYRK family of protein kinases. Mirk contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions [taken from NCBI Entrez Gene (GeneID: 9149)].
Description (Vector)
DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.
Gene ID
9149
Gene Name (eCommerce)
dual specificity tyrosine phosphorylation regulated kinase 1B
Gene Name (Vector)
dual specificity tyrosine phosphorylation regulated kinase 1B
Gene Symbol
DYRK1B
HGNC ID
HGNC:3092
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1890
ORF Size (bp)
1890 bp
Protein Name (eCommerce)
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
RefSeq ID
NM_004714
RefSeq Synonyms
NM_006484, NM_006483, NM_004714, BC025291, BC018751,
Research Areas
EGFR Signaling,Immunology,Kinase/Phosphatase,Signal Transduction,T-cell Receptor Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
Minibrain-related kinase (mirk) is also known as DYRK1B (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B). Mirk is a member of the DYRK family of protein kinases. Mirk contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions [taken from NCBI Entrez Gene (GeneID: 9149)].
UniGene ID
Hs.130988
UniProt ID (eCommerce)
Q9Y463
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.